Asymmetric organotellurium hard-soft donor schiff base ligand and its Cu(II)/Ni(II) complexes: DNA intercalation, anti-inflammatory and antimicrobial activity

Polyhedron · 2026-05-12

Long-term Kinetics of Vibriocidal Antibody Responses After <i>Vibrio cholerae</i> Infection in the Democratic Republic of Congo

The Journal of Infectious Diseases · 2025-07-22 · 1 citations

Interpretation of seroepidemiology studies of cholera relies on knowledge of antibody kinetics, which are not well known in African populations. We performed vibriocidal antibody assays on 212 serum samples from 115 patients with culture-positive cholera (median age, 8 years) in Goma, Democratic Republic of Congo, which were collected at enrollment and 3 to 449 days after. Vibriocidal responses peaked at 7 to 40 days after symptom onset, with 89.5% waning to a titer ≤160 by 180 days. We used a bayesian exponential decay model to show an 88% probability of the posterior distribution supporting a faster decay in children ≤5 years of age.

Therapeutic and structural insights into selenium bearing inflammatory inhibitors and DNA intercalators

Journal of Molecular Structure · 2025-05-23 · 1 citations

The addition of natural clay and industrial and agricultural waste on the performance of green and sustainable concrete

Scientific Reports · 2025-05-16 · 11 citations

emissions, necessitating the development of sustainable alternatives such as fiber-reinforced concrete incorporating supplementary cementing materials (SCMs) and agricultural waste. This approach keeps the environment safe by reducing the consumption of conventional raw materials for concrete production. Incorporating the SCMs in concrete can potentially improve the mechanical and durability properties. This research evaluated the behavior of concrete mixtures using different proportions of natural wheat straw fiber, bentonite, and silica fume (SF). The fresh property was investigated by using a workability test, and mechanical properties were investigated by using compressive strength and split tensile strength. Bulk density, water absorption, and sorptivity tests were also performed to investigate the durability of concrete. Scanning electron microscopy (SEM) was conducted to evaluate the microstructure and morphology of the developed concrete mixtures. The results revealed that the slump value decreased with incorporating SCMs and fibers (83-42 mm). The compressive strength ranged from 11 MPa to 23 MPa, increasing with the increased Bentonite and SF dosages. Splitting tensile strength ranged from 2.2 MPa to 2.7 MPa, showing an increase with increased dosages of SCMs and fibers. The addition of WSFR compromised the compressive strengths of the developed mixtures, however, the ductility of the mixtures was improved with the incorporation of the WSFR. The SEM confirmed the CSH gel formation in the mixtures containing bentonite and SF. This gel formation improved the mechanical properties of the concrete, reduced water absorption, and increased its resistance to acid. The resulting concrete mixtures can address the carbon emissions associated with cement production and provide a sustainable construction material.

Defect-Mediated Improved Electrochemical Performance of Wo3 Incorporated Mns Hetero-Nancomposites for Supercapacitor Electrodes in Ionic Electrolytes

SSRN Electronic Journal · 2025-01-01

COMPARATIVE EVALUATION OF ENVIRONMENTAL IMPACT ASSESSMENT SYSTEMS IN THE UNITED KINGDOM AND PAKISTAN

Pakistan Journal of Science · 2025-03-15

Environmental Impact Assessment (EIA) is a vital instrument for fostering sustainable development ensuring the identification, evaluation, and mitigation of impacts on the environment caused by developmental projects. In comparison, developed countries like the United Kingdom (UK) have a well-established EIA framework as a mandatory practice contradictory to developing nations like Pakistan, who are still striving to strengthen the EIA process. Despite this status of development, both countries share the global responsibility of preserving the environment. The current research critically compares the EIA evaluation methods in the UK and Pakistan by examining the Environmental Statements (EA) from the UK and baseline studies from Pakistan. It focuses on the areas where the system differs by analyzing essential steps such as screening, scoping, alternative analysis, EIA report preparation, decision-making, and monitoring. Wood's Model and Lee and Colley's (1992) Review Package are employed to evaluate the quality of the EIA conducting process. Findings indicate that the UK‘s EIA framework is robust and effectively integrated into project planning to ensure informed decision-making. While Pakistan‘s EIA framework, in contrast, is facing challenges such as technical deficiencies and weak enforcement, leading to limited capacity in assessing and addressing environmental impacts. Focus on the gaps in Pakistan‘s EIA framework is crucial in aligning with international standards to achieve sustainable development by embracing lessons from the UK.

Pendent Amine Group at the Outer Coordination Sphere of a Copper(II) Complex Enhances the Rate of Oxygen Reduction Reaction

Small · 2025-07-10

Abstract Enhancing the rate of an electrocatalytic reaction through the strategic incorporation of secondary coordination sphere (SCS) interactions—such as hydrogen bonding, proton relays, and electrostatic effects—is a critical factor influencing both turnover frequency (TOF) and overpotential. In this study, the oxygen reduction reaction (ORR) is investigated using two Cu(II) complexes ( 1 and 2 ) supported by a bis‐pyridine‐dioxime ligand framework. Complex 2 features an o–NMe 2 –C 6 H 4 – substituent in the SCS. Comparative electrocatalytic ORR studies of 1 and 2 in phosphate buffer revealed that 2 exhibited ≈3 times higher TOF than 1 . Similarly, ORR studies in acetonitrile in the presence of trifluoroacetic acid (TFAH) and decamethylferrocene (Fc * ) showed that 2 is about twice as active as 1 . Based on the kinetic investigations, it is suggested that reduction of a Cu II (O 2 • ) intermediate occurs during the rate‐determining step (rds) for complex 1 in acetonitrile, whereas a different rds is noted for complex 2 , which is the protonation of the Cu II (O 2 • ). Overall, this study underscores the pivotal role of SCS interactions in accelerating ORR and represents one of the few reports detailing the influence of the outer coordination sphere on ORR catalyzed by molecular Cu complexes.

Defect-mediated improved electrochemical performance of WO3 incorporated MnS hetero-nanocomposites for supercapacitor electrodes in ionic electrolytes

Journal of Physics and Chemistry of Solids · 2025-06-25 · 2 citations

Cholera risk in Goma, DR Congo, after forced clearing of relief camps

The Lancet · 2025-04-29 · 1 citations

Redox Non‐Innocent Ligand Assisted Electrocatalytic Water Oxidation Catalyzed by a Molecular Cobalt Complex

ChemCatChem · 2025-04-16 · 5 citations

Abstract Redox‐non innocent ligands play a crucial role in multielectron catalysis by participating in oxidation or reduction processes. High‐valent metal ions are often involved in oxidative catalysis, such as the water oxidation (WO) reaction, acting as a site for electron extraction from the substrate. Redox‐active ligands featuring multiple electron transfer centers can serve a similar function in catalysis. In this study, we explore the electrocatalytic WO reaction using a molecular Co III complex ( 1 ) that incorporates a bis‐pyridine‐dioxime ligand scaffold. This complex acts as a homogeneous electrocatalyst for WO in phosphate buffer solution (PBS) over a wide pH range. At pH 7, 1 demonstrated an overpotential of ∼590 mV and a turnover frequency of 16 s⁻¹. We propose that the oxime and C 6 H 5 –NR 2 arm of the ligand function as a redox cofactor, facilitating the catalysis and highlighting an important strategy for developing WO catalysts. However, in a borate buffer solution (BBS) degradation of 1 was noted accompanied by the deposition of B/CoO x material on the working electrode.