Adrienne M. Antonson

About

Dr. Adrienne M. Antonson is an Assistant Professor of Animal Sciences at the University of Illinois Urbana-Champaign, where she leads the Antonson Developmental Neuroimmunology Laboratory. She completed her PhD in Animal Science, specializing in Immunophysiology and Behavior, at the University of Illinois Urbana-Champaign from 2013 to 2018. Following her doctoral studies, she pursued postdoctoral research at the Institute for Behavioral Medicine Research at The Ohio State University from 2018 to 2021. Dr. Antonson's academic background combines biology and animal sciences with a focus on neuroimmunology, reflecting her interdisciplinary expertise in these areas. Originally from Chatham, New York, Dr. Antonson balances her professional work with personal interests such as running, hiking, cycling, mountain biking, and enjoying local brews. She also enjoys listening to true crime podcasts, reading, cooking, and caring for her two cats. A fun personal note is that she has a twin sister named Hannah who lives in Austin, Texas.

Research topics

• Biology
• Neuroscience
• Internal medicine
• Genetics
• Medicine
• Endocrinology
• Immunology
• Psychology
• Bioinformatics

Selected publications

• At the crux of maternal immune activation: Viruses, microglia, microbes, and <scp>IL‐17A</scp>

  Immunological Reviews · 2022-08-18 · 47 citations

  reviewOpen accessSenior authorCorresponding

  Inflammation during prenatal development can be detrimental to neurodevelopmental processes, increasing the risk of neuropsychiatric disorders. Prenatal exposure to maternal viral infection during pregnancy is a leading environmental risk factor for manifestation of these disorders. Preclinical animal models of maternal immune activation (MIA), established to investigate this link, have revealed common immune and microbial signaling pathways that link mother and fetus and set the tone for prenat…

  PublisherOA PDFDOI

• Lasting and Sex-Dependent Impact of Maternal Immune Activation on Molecular Pathways of the Amygdala

  Frontiers in Neuroscience · 2020 · 35 citations

  The prolonged and sex-dependent impact of maternal immune activation (MIA) during gestation on the molecular pathways of the amygdala, a brain region that influences social, emotional, and other behaviors, is only partially understood. To address this gap, we investigated the effects of viral-elicited MIA during gestation on the amygdala transcriptome of pigs, a species of high molecular and developmental homology to humans. Gene expression levels were measured using RNA-Seq on the amygdala for…

  DOI

• Moderately pathogenic maternal influenza A virus infection disrupts placental integrity but spares the fetal brain

  Brain Behavior and Immunity · 2021-05-12 · 27 citations

  articleOpen access1st authorCorresponding
  PublisherOA PDFDOI

• Interacting impact of maternal inflammatory response and stress on the amygdala transcriptome of pigs

  G3 Genes Genomes Genetics · 2021-04-15 · 24 citations

  articleOpen access

  Changes at the molecular level capacitate the plasticity displayed by the brain in response to stress stimuli. Weaning stress can trigger molecular changes that influence the physiology of the offspring. Likewise, maternal immune activation (MIA) during gestation has been associated with behavior disorders and molecular changes in the amygdala of the offspring. This study advances the understanding of the effects of pre- and postnatal stressors in amygdala gene networks. The amygdala transcripto…

  PublisherOA PDFDOI

• Influenza A virus during pregnancy disrupts maternal intestinal immunity and fetal cortical development in a dose- and time-dependent manner

  Molecular Psychiatry · 2024-07-03 · 19 citations

  articleOpen accessSenior author

  Abstract Epidemiological studies link exposure to viral infection during pregnancy, including influenza A virus (IAV) infection, with increased incidence of neurodevelopmental disorders (NDDs) in offspring. Models of maternal immune activation (MIA) using viral mimetics demonstrate that activation of maternal intestinal T helper 17 (T H 17) cells, which produce effector cytokine interleukin (IL)-17, leads to aberrant fetal brain development, such as neocortical malformations. Fetal microglia and…

  PublisherOA PDFDOI

Frequent coauthors

• Tamar Gur

  The Ohio State University Wexner Medical Center

  38 shared

• Helen J. Chen

  The Ohio State University Wexner Medical Center

  29 shared

• Michael T. Bailey

  The Ohio State University Wexner Medical Center

  18 shared

• Rodney W. Johnson

  University of Illinois Urbana-Champaign

  14 shared

• Therese Rajasekera

  Institute for Behavioral Medicine

  14 shared

• Jeffrey D. Galley

  The Ohio State University Wexner Medical Center

  14 shared

• Sydney Lammers

  13 shared

• Ashley Otero

  University of Illinois Urbana-Champaign

  9 shared

Education

• PhD, Animal Sciences

  University of Illinois at Urbana-Champaign

  2018

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