The soldier and the exorcist:

Archaeopress Publishing Ltd eBooks · 2025-05-29

P147 Endoscopically-delivered purastat to treat haemorrhagic radiation proctopathy is safe, feasible and well-tolerated: results from a randomised feasibility study

2025-06-01

Chapter 5: A New Interpretation of Ministry: John N. Collins on Diakonia

Rowman & Littlefield Publishers eBooks · 2025-01-01

Pouch excision, dysplasia and polypectomy in familial adenomatous polyposis ileal pouch anal anastomosis: a retrospective analysis

BMJ Open Gastroenterology · 2025-12-01

INTRODUCTION: Familial adenomatous polyposis (FAP) is a rare autosomal dominant syndrome that, if untreated, carries a 100% lifetime risk of developing colorectal cancer. Proctocolectomy with ileal pouch-anal anastomosis (IPAA) is a surgical approach for FAP management, but data on long-term outcomes remain limited. This study aimed to assess IPAA-associated pouch excision, dysplasia, polyp management and pouchitis in patients with FAP post IPAA. METHODS: Single-centre retrospective review of patients with FAP with IPAA at a tertiary referral centre. Data on demographics, pouch excision, endoscopic and histopathological records were collected. Statistical analysis was performed using Excel and GraphPad. RESULTS: Forty patients with FAP with IPAA were included. The median age was 48 years (IQR 33-58.5), with a median age of 22 years at pouch formation (IQR 18-30.5) and a median pouch age of 217 months (IQR 143-279). A total of 230 lower gastrointestinal endoscopies were assessed. Low-grade dysplasia was identified in 70 endoscopies, and polyps in 82, with the pouch being the most common site. One case of rectal adenocarcinoma was identified, with no cases of high-grade dysplasia. There were 35 episodes involving polypectomy, with cold snare being the most common method (50%). Endoscopic management had a lower complication rate than surgical management (p=0.0474). Eight (20%) patients underwent pouch excision, with poor function being as common as pouch-related complications (37.5%), with a median pouch age at excision of 167 months (IQR 115.5-286.5). Endoscopic pouchitis was significantly more common in those who underwent pouch excision (p=0.0231). CONCLUSION: Patients with FAP and IPAA require surveillance due to a high incidence of dysplasia and polyp formation, although malignancy remains rare. There is a significant rate of pouch excision, for which pouchitis appears to be a risk factor. Early and aggressive endoscopic management of polyps is recommended to prevent advanced disease and minimise complications associated with surgical approaches.

Assessing positional and dosimetric performance of a Elekta Versa HD linac in clinical VMAT techniques

Physica Medica · 2025-10-01

Protein-losing enteropathies

Frontline Gastroenterology · 2025-07-23

Protein-losing enteropathy (PLE) is a syndrome in which there is a non-selective loss of protein into the lumen of the gastrointestinal (GI) tract. It is identified by increased alpha-1 antitrypsin excretion in the stool. There are many diseases, both congenital and acquired, that can lead to PLE. Diseases may exhibit features of PLE as a consequence of intestinal mucosal disease or impairment of lymphatic drainage from the GI tract. PLE should be considered when hypoproteinaemia occurs in patients in whom other causes of protein loss and reduced synthetic function have been excluded. Patients with PLE typically develop hypoproteinaemia and peripheral oedema. The reduction in oncotic pressure may also lead to pericardial or pleural effusions. Other clinical features can vary depending on the underlying cause. Patients with PLE may develop severe nutritional deficiencies. This review outlines a strategy of investigating PLE. Management is targeted towards treatment of the underlying condition, correction of fluid and electrolytes and management of nutritional deficiency.

Chapter 6: The Contemporary Priesthood and Ministry

Rowman & Littlefield Publishers eBooks · 2025-01-01

Chapter 2: The Priesthood from the New Testament to the Reformation

Rowman & Littlefield Publishers eBooks · 2025-01-01

ENDOSCOPICALLY-DELIVERED PURASTAT FOR THE TREATMENT OF HAEMORRHAGIC RADIATION PROCTOPATHY IS SAFE, FEASIBLE AND WELL TOLERATED: RESULTS FROM A RANDOMISED FEASIBILITY STUDY

Gastrointestinal Endoscopy · 2025-05-01

The Educational Journeys of a Boomer and Gen X'er

IGI Global eBooks · 2025-06-06

This chapter is a reflective analysis centered on the personal narratives of educational experiences of two Black male educators who have served over five decades combined at multiple levels in K-12 schools and as university faculty. One of the Black male educators is a U.S. Baby Boomer (1946 – 1964). The other Black male educator was born between 1965 and 1980, commonly called Generation X (Gen X). Highlighting the notion that Black lives matter in the historical ‘then' and the contemporary ‘now' is significant as it pertains to addressing the interests and needs of African American students in US public education and, by extension, the general society. Using an autoethnographic approach to analyze the historical intersections of personal experience and broader cultural phenomena, four themes emerged from the reflective personal narratives: (a) the challenges and confrontations of Black and White students, (b) generational poverty for Black students in the South, (c) lost traditions and dispossession, and (d) having to be twice as good to be considered average.