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Joshua Lorenz

Joshua Lorenz

· Assistant Professor of Radiation and Cellular OncologyVerified

University of Chicago · Pharmacology

Active 1967–2026

h-index34
Citations3.7k
Papers13215 last 5y
Funding
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About

Joshua Lorenz is an Assistant Professor of Radiation and Cellular Oncology at the Biological Sciences Division of the University of Chicago. His clinical interests include breast cancer, gastrointestinal cancers, head and neck cancer, and lung cancer. He is affiliated with UChicago Medicine and the Pritzker School of Medicine. Further information about his research network profile and contact details are available through the university's channels.

Research topics

  • Medicine
  • Radiology
  • Nuclear medicine
  • Internal medicine
  • Surgery

Selected publications

  • Abstract No. 523 Transhepatic Access Closure for Islet Cell Transplant in Anticoagulated Patients: A Comparison of Microfibrillar Collagen Paste, Coils, and Coil Plus Gelfoam

    Journal of Vascular and Interventional Radiology · 2026-03-23

    article
  • Occult Hepatic Artery Infusion Pump Anastomosis Leak Treated with Stent

    Journal of Vascular and Interventional Radiology · 2026-04-02

    article
  • Abstract No. 28 Angiographic Embolization for Treatment of Thoracic Wall Hemorrhage: A Single Institution Study

    Journal of Vascular and Interventional Radiology · 2026-03-23

    articleSenior author
  • Interventional Radiology Management of the Acute Trauma Patient

    Digestive Disease Interventions · 2025-05-02

    articleSenior author

    Abstract The management of traumatic injuries requires the coordinated efforts of a multidisciplinary team of trauma surgeons, subsurgical specialties, intensivists, and interventionalists. The interventional radiologist plays a critical role in the management of acute trauma by offering 24-hour consultation, expert imaging interpretation, and an array of life-saving minimally invasive procedures. As integrated members of the multidisciplinary clinical team, the interventional radiologist should be able to review clinical information, communicate clearly with consulting services, perform timely intervention, provide postprocedural follow-up, and document relevant information in the patient chart. The following review provides a stepwise approach to the rapid clinical assessment of the trauma patient and outlines the pathways taken by the trauma patient to the interventional radiology suite.

  • Transhepatic access closure for islet cell transplant in anticoagulated patients: a comparison of microfibrillar collagen paste, coils, and coil plus gel foam

    CVIR Endovascular · 2025-12-09

    articleOpen access

    PURPOSE: To evaluate the safety and effectiveness of microfibrillar collagen paste (MCP), coils, and coils combined with gelatin sponge for transhepatic access tract embolization following portal vein islet cell transplant. METHODS: A retrospective review was conducted at a single institution between January 2008 and October 2024, including 20, 28, and 21 consecutive islet cell transplant procedures requiring transhepatic access embolization with MCP, coils, and coil plus gelatin sponge, respectively. All procedures were performed via a right portal vein branch. MCP was performed using Avitene (BD). The average number of coils required in the coil plus gelatin sponge and coil-only groups were 1.8 and 1.6 coils per procedure, respectively. All patients were placed on therapeutic anticoagulation during the procedure and for at least two weeks post-transplant. Medical records were reviewed to compare laboratory results, portal venous pressures, post-procedure liver ultrasounds, and 30-day hemorrhagic events across the three groups. RESULTS: All procedures were technically successful. However, one instance of coil migration into a portal vein branch occurred in the coil plus gelatin sponge group (1/28, 3.5%). Baseline hemoglobin, platelet counts, and partial thromboplastin time did not differ significantly between groups (p > 0.05). A statistically significant lower international normalized ratio (INR) was observed in the MCP group compared to the gelatin sponge and coil-only groups (1.0 vs. 1.1 vs. 1.1, p = 0.0036 and 0.004). No statistically significant differences were found in hemoglobin changes, post-transplant portal venous pressures, or post-embolization hemorrhagic events (p > 0.05). One patient in the coil plus gelatin sponge group developed a large subcapsular hematoma (1/27, 3.7%), while another in the MCP group experienced a large right hemothorax (1/20, 5.0%). CONCLUSION: MCP, coils, and coil plus gelatin sponge are similarly effective for transhepatic access closure following islet cell transplant in anticoagulated patients. However, coil embolization may require multiple coils and carries a risk of migration.

  • TIPS Revision: Indications, Techniques, and What to Consider When Revision Fails

    Techniques in vascular and interventional radiology · 2025-10-04

    articleOpen access

    To review the current indications, surveillance strategies, and technical approaches for transjugular intrahepatic portosystemic shunt (TIPS) revision, with emphasis on ultrasound surveillance limitations, surveillance models, and management of refractory complications, including novel approaches such as parallel TIPS. Comprehensive review of current literature on TIPS revision procedures, surveillance protocols, and management of TIPS-related complications. TIPS dysfunction occurs in 10%-20% of patients within the first year despite covered stent technology. Ultrasound surveillance remains the cornerstone of monitoring but has significant limitations. Novel approaches including parallel TIPS placement and advanced management strategies for refractory ascites show promising results. TIPS revision requires careful patient selection, optimized surveillance protocols, and advanced technical expertise. Emerging technologies and treatment paradigms continue to evolve, improving outcomes for patients with complex portal hypertensive complications.

  • Endovascular Management of Noncirrhotic Acute Portomesenteric Venous Thrombosis

    Journal of Vascular and Interventional Radiology · 2024-10-09 · 4 citations

    review1st authorCorresponding
  • Dispelling the Myths of Percutaneous Catheter Drainage of Infected Abdominal Collections

    Seminars in Interventional Radiology · 2024-10-01

    reviewOpen access1st authorCorresponding

    When consulted for percutaneous catheter drainage (PCD) of abdominopelvic collections, interventional radiologists (IRs) should consider the appropriateness of this technique in the context of other options such as conservative, endoscopic, or surgical management. Whenever possible, published data should be considered prior to performing percutaneous drainage, especially as regards controversial scenarios such as the use of fibrinolytic therapy, the primary placement of large-bore drainage catheters, the drainage of cystic tumors, the drainage of splenic abscesses, and the treatment of collections lacking an in-line drainage window. This article examines past and present published data on PCD to dispel some common myths and guide IRs toward the best applications of PCD.

  • Endovascular Retrieval of a Damaged Transjugular Intrahepatic Portosystemic Shunt Stent Graft

    Journal of Vascular and Interventional Radiology · 2024-02-26 · 1 citations

    letterOpen access
  • Direct intrahepatic portocaval shunt compressing the bile duct: a rare case of jaundice

    Gastrointestinal Endoscopy · 2023-11-22

    article

Frequent coauthors

  • Brian Funaki

    University of Chicago Medical Center

    59 shared
  • Baljendra Kapoor

    University of Michigan–Ann Arbor

    26 shared
  • Jeffrey A. Leef

    23 shared
  • Rakesh Navuluri

    University of Chicago

    19 shared
  • Thuong Van Ha

    University of Chicago Medical Center

    18 shared
  • Steven Zangan

    University of Chicago

    17 shared
  • Giovanni Mauri

    European Institute of Oncology

    16 shared
  • Eric J. Hohenwalter

    Medical College of Wisconsin

    15 shared

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