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Indra K. Reddy

Indra K. Reddy

· Professor of Pharmaceutical SciencesVerified

Texas A&M University · Pharmaceutical Sciences

Active 1994–2025

h-index29
Citations3.4k
Papers938 last 5y
Funding
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About

Professor Indra K. Reddy is the Founding Dean of the Irma Lerma Rangel College of Pharmacy and serves as the Interim Chief Operating Officer & Senior Vice President of Texas A&M Health. He holds a PhD and is a Fellow of the American Association of Pharmaceutical Scientists (FAAPS) and the American Pharmacists Association (FAPhA). His personal journey as a first-generation college graduate from a small rural town in India, where his early life was marked by adversity including the loss of his father at age 12, has profoundly shaped his perspective and dedication to education. Reddy's story emphasizes the importance of dreaming big, working relentlessly, and the transformative power of education. His background includes completing his bachelor's, master's, and doctoral degrees, and he advocates for the significance of perseverance and discipline in achieving academic and professional success. His leadership at the college underscores a commitment to supporting first-generation students and fostering an environment where future healthcare professionals can thrive.

Research topics

  • Chemistry
  • Sociology
  • Medicine
  • Chromatography
  • Organic chemistry
  • Gender studies
  • Psychology
  • Medical education
  • Social psychology
  • Internal medicine
  • Pedagogy
  • Pharmacology
  • Biochemistry

Selected publications

  • A Comparative Study in Metformin Tablet Quality Assessment: LC‐MS and LC‐MS/MS Method Quantification of N‐Nitroso‐Dimethylamine in the Presence of Dimethyl Formamide

    International Journal of Analytical Chemistry · 2025-01-01

    articleOpen access

    N‐nitroso‐dimethylamine (NDMA, acceptable daily intake limit 96 ng/day), a probable human carcinogenic impurity, has been reported in metformin formulations. In some cases, it is difficult to accurately detect its presence due to suboptimal extraction technique(s), coelution of other probable human carcinogenic impurities such as dimethyl formamide (DMF) and/or ionization suppression in mass spectroscopic measurements. In this study, we provided a simple method to address DMF artifact using an affordable high‐performance liquid chromatography coupled with a single‐stage mass spectrometer. The results were further confirmed by dual‐stage mass spectrometry. The two developed methods can simultaneously identify NDMA in the presence of DMF with good linear range from 10 to 100 ng/mL ( r 2 = 0.971) and 1 to 10 ng/mL ( r 2 = 0.994), respectively. The accuracy, expressed as % recovery, was close to 100% with overall precision (%RSD) < 8. The two methods were linear in the presence of 100 ng/mL DMF with r 2 = 0.996 and 0.98, respectively. Five commercial formulations of metformin tablets showed traces of NDMA below the regulatory limit (0–12 ± 0.2 ng/tablet) but appreciable amounts of DMF (50–653.5 ng/tablet), still lower than the permissible daily exposure limit (8.8 mg/day) based on the maximum daily dose of metformin (5 tablets, 2500 mg). Both methods proved reliable and informative in the quality control of the NDMA content in metformin tablets and provided reciprocal verification of results.

  • Securing Wireless Sensor Networks with an Intrusion Detection Technique Based on Grid Search Random Forest and Modified Feature Selection Technique

    2024-10-25

    article

    Sensor networks (WSNs) are fundamental components of multi-hop cyberphysical systems, incorporating stationary and mobile components. There are, however, many attacks that can disrupt the operation of WSNs and compromise security. This paper presents an Intrusion Detection System (IDS) framework that utilizes Grid Search Random Forest algorithms along with Boruta feature selection to meet these challenges. With this framework, WSN intrusions will be detected more accurately. Two benchmark datasets are used in the framework, NSL-KDD and CICIDS2017, representing different scenarios of network intrusion. Data are preprocessed through the use of Morphological Filtering and Extended Empirical Wavelet Transform, which eliminates noise and irrelevant features from the data. As a result of this preprocessing step, the model will be able to detect more accurately.

  • ALFP Debate: Tiered Training and Licensure as a Model for the Future of Pharmacy Education

    American Journal of Pharmaceutical Education · 2024-09-01

    articleOpen accessSenior author
  • A Qualitative Study of Underrepresented Minority (URM) Student Pharmacists’ Intersectionality and Professional Identity Formation

    American Journal of Pharmaceutical Education · 2023 · 4 citations

    Senior authorCorresponding
    • Sociology
    • Psychology
    • Pedagogy

    OBJECTIVE: To determine how underrepresented minority (URM) student pharmacists' intersectionality affects professional identity formation early in their academic career. METHODS: A qualitative study was undertaken. All students from Classes 2022 through 2025 at Texas A&M University School of Pharmacy were required to engage in reflection on a personal statement of philosophy of practice early in their first year of pharmacy as part of the structured longitudinal co-curricular course requirement. Statements of the URM students who referenced their intersecting identities were selected for deductive analysis per Bingham and Witkowsky and inductive analysis using Lincoln and Guba's approach to content analysis. RESULTS: Of the 221 URM student pharmacists within the 4 cohorts who submitted a statement, 38 statements (92% Hispanic students) met the inclusion criteria. Student hometowns and the identity domains of the individual, relational, and collective were selected a priori for the deductive analysis. Students most often referenced individual identity characteristics that fit under the Principles I, IV, V, and VII of the Code of Ethics for Pharmacists. Three themes emerged from the inductive analysis: (1) defining experiences and resulting realizations, (2) motivating forces, and (3) aspirations as a pharmacist. A working hypothesis was developed. CONCLUSION: The URM students' intersecting identities (race, ethnicity, socioeconomic class, and belonging to an underserved community) influenced their early professional identity formation. The desire to bring about racial uplift was observed among the Hispanic students as early in their P1 year through the School's required co-curricular reflection. Such reflective practice serves as an effective vehicle for the students to recognize their intersecting identities that impact their professional identity.

  • In-use stability assessment of FDA approved metformin immediate release and extended release products for N-Nitrosodimethylamine and dissolution quality attributes

    International Journal of Pharmaceutics · 2022 · 17 citations

    • Pharmacology
    • Chemistry
    • Medicine
  • Strategies for the integration of foundational and clinical sciences in doctor of pharmacy programs

    JACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY · 2021-06-30 · 4 citations

    article

    Abstract Introduction Enhancing the integration of foundational and pharmaceutical sciences with the clinical pharmacy curriculum will develop practitioner‐scholar pharmacists. However, implementing and assessing integration is challenging. Hindrance factors include limited pragmatic approaches, the lack of a “how‐to” blueprint, faculty and student resistance to change, compression of pharmaceutical science teaching, and a paucity of assessment strategies. Methods This study examined the history, theory, and practice of integration and utilization of the 2013 Center for Advancement of Pharmacy Education (CAPE) Outcomes to achieve integration in Doctor of Pharmacy (PharmD) programs. For this, 252 faculty members across the American Association of Colleges of Pharmacy (AACP) Biological Sciences, Pharmaceutics, and Chemistry sections were surveyed to assess faculty perception regarding (1) the importance of integrating foundational and clinical sciences, (2) the extent, and (3) intentionality of incorporation of the 2013 CAPE Outcomes in the foundational sciences. The 2013 CAPE Outcomes perceived to be challenging to incorporate into the foundational sciences were identified. Subsequently, strategies for integration and assessment grounded in educational theories were developed. Results Patient advocacy (CAPE 3.3), cultural sensitivity (CAPE 3.5), innovation and entrepreneurship (CAPE 4.3), medication use management (CAPE 2.2), self‐awareness (CAPE 4.1), and leadership (CAPE 4.2) received scores suggesting limited incorporation in foundational sciences. To address this, examples of integration strategies were shown based on these 2013 CAPE Outcomes to enhance foundational science bridging with clinical and practice pharmacy education. Curricular models such as the McMaster method, H and Z stack approaches, and the Harden's Ladder as an assessment tool to measure curricular integration are examined in the context of the 2013 CAPE Outcomes, grounded in educational theory. Conclusion This work summarizes the recommendations of the AACP Biological Sciences Section Task Force for examples of methods for achieving, augmenting, and assessing the integration of pharmaceutical and foundational sciences with clinical practice in PharmD programs.

  • Preparation and characterization of dicarboxylic acids salt of aripiprazole with enhanced physicochemical properties

    Pharmaceutical Development and Technology · 2021 · 12 citations

    • Chemistry
    • Organic chemistry

    The focus of present work was to prepare salt of aripiprazole (APZ) with dicarboxylic acids to improve physicochemical properties the drug. Dicarboxylic acids used in the study were malonic acid, maleic acid and succinic acid. The salts were prepared with solubilization-crystallization method. The salts were characterized for pH-solubility, dissolution, and stabilities. The Fourier infrared spectroscopy, X-ray powder diffraction, differential scanning calorimetry and near infrared chemical imaging indicated formation of new solid phase. pH-solubility profiles of the salts were similar to the drug except higher solubility were observed in the salts at all tested pH. The highest solubility was observed for APZ-Malonate salt among all the prepared salts. The solubility curve was inverted 'V' shape for APZ-maleate and APZ-succinate while it was inverted 'U' shape for APZ-malonate. The water solubility of APZ, APZ-malonate, APZ-maleate and APZ-succinate were 0.07 ± 0.02, 3503.9 ± 37.4, 269.3 ± 6.9 and 729.4 ± 9.4 µg/mL, respectively. The dissolution was 2.9 ± 0.4, 18.4 ± 3.9, 19.5 ± 1.4 and 36.6 ± 4.0% in 45 min for APZ, APZ-maleate, APZ-malonate, and APZ-succinate. The stabilities of the salts were similar to the drug. Thus, salts improved the physicochemical properties of the drug, and have similar stability profiles as that of APZ.

  • Additive Manufacturing with 3D Printing: Progress from Bench to Bedside

    The AAPS Journal · 2018-09-12 · 143 citations

    review
  • Effect of processing parameters and controlled environment storage on the disproportionation and dissolution of extended-release capsule of phenytoin sodium

    International Journal of Pharmaceutics · 2018-07-19 · 24 citations

    article
  • Nanotechnology-based drug products

    Elsevier eBooks · 2018-01-01 · 13 citations

    book-chapter

Frequent coauthors

Labs

  • Pharmaceutical SciencesPI

Education

  • Ph.D., Pharmaceutical Sciences

    University of Florida

    1989
  • M.S., Pharmacy (Pharmaceutics)

    Dr Hari Singh Gour University

    1984
  • B.Pharm, College of Pharmaceutical Sciences

    Kakatiya University

    1981

Awards & honors

  • Presidential Impact Fellow
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