Jogender Tushir-Singh
· Associate ProfessorUniversity of California, Davis · Dermatology
Active 2016–2024
About
Jogender Tushir-Singh, Ph.D., is an Associate Professor in the Department of Microbiology & Immunology at UC Davis. His research focuses on using protein engineering and multi-targeting antibodies in the context of human cancers and other pathologies. He is particularly interested in targeting the differential clinical response of immunotherapies and chimeric-antigen receptor (CAR) cells in solid versus liquid tumors. His recent work involves unraveling unusual apoptotic regulatory motifs and immunomodulatory cancer signaling pathways downstream of solid tumor enriched death receptor-5 (DR5). Dr. Tushir-Singh extensively uses ovarian and triple-negative breast cancer (TNBC) models to test hypothesis-driven tumor therapeutics approaches. Additionally, he explores dual-specificity CAR targeting strategies in ovarian and TNBC models, along with SARS-CoV-2 spike processing inhibition strategies in viral-producing cells.
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