Janet Best
VerifiedOhio State University · Mathematics
Active 2005–2024
Research topics
- Pharmacology
- Medicine
- Internal medicine
- Neuroscience
- Endocrinology
- Psychology
Selected publications
Serotonin is a common thread linking different classes of antidepressants
Cell chemical biology · 2023 · 14 citations
- Pharmacology
- Psychology
- Neuroscience
Journal of Neuroscience · 2021 · 57 citations
- Pharmacology
- Internal medicine
- Endocrinology
Acute LPS-induced inflammation (1) increases CNS histamine, (2) decreases CNS serotonin (via inhibitory histamine receptors), and (3) prevents a selective serotonin reuptake inhibitor (SSRI) from effectively increasing extracellular serotonin. A targeted depletion of histamine recovers SSRI-induced increases in extracellular hippocampal serotonin.
Recent grants
CAREER: Mathematical Questions Arising from Neural Systems - Research and Education
NSF · $405k · 2010–2016
Mathematical Biosciences Institute
NSF · $8.2M · 2015–2021
Frequent coauthors
- 38 shared
Michael C. Reed
Duke University
- 38 shared
Parastoo Hashemi
Imperial College London
- 18 shared
Sergio Mena
Imperial College London
- 17 shared
H. Frederik Nijhout
Duke University
- 15 shared
H. Frederik Nijhout
Duke University
- 13 shared
Ian Bain
- 13 shared
Melinda Hersey
National Institute on Drug Abuse
- 12 shared
Thorsten Lau
German Cancer Research Center
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