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Suqin Guo

Suqin Guo

· ProfessorVerified

Rutgers University · Ophthalmology and Visual Science

Active 1989–2024

h-index16
Citations1.5k
Papers10035 last 5y
Funding
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About

Dr. Suqin Guo is a Professor at Rutgers New Jersey Medical School and serves as the Director of Medical Student Education. She graduated from Inner Mongolia Medical School in China with a Doctor of Medicine degree and earned a Master of Medical Science degree from Beijing Medical School. Dr. Guo completed her residency at the former UMDNJ in Newark, NJ, and has completed two pediatric fellowships, one at The Eye Center at Emory University in Atlanta, GA, and the other at Wills Eye Hospital in Philadelphia, PA. She specializes in Pediatric ophthalmology and strabismus as well as cataract surgery. Her research and clinical expertise focus on pediatric ophthalmology, strabismus, anterior segment, and cataract surgery, with numerous publications in these areas.

Research topics

  • Internal medicine
  • Medicine
  • Psychiatry
  • Audiology
  • Psychology
  • Biology
  • Ophthalmology
  • Neuroscience
  • Surgery
  • Radiology
  • Cardiology
  • Genetics

Selected publications

  • Comparison of single-chain variable fragments and monoclonal antibody against dihydroartemisinin

    Journal of Immunological Methods · 2024-07-24 · 1 citations

    articleSenior authorCorresponding
  • [The relationship between auditory verbal hallucination and gray matter volume and cortical thicknessin first-episode childhood-onset schizophrenia].

    PubMed · 2024-12-03

    articleSenior author

    The decreased gray matter volume and cortical thickness is found in multiple brain regions in with or without auditory verbal hallucination in first-episode childhood-onset schizophrenia. Consequently, abnormal gray matter structure may be associated with the pathogenesis of childhood schizophrenia.The abnormal structure of the left and right superior temporal grrus, right supramarginal gyrus, right anterior cingulate cortex may be related to the mechanism of auditory hallucination.

  • [Topological properties of white matter network in first untreated children and adolescents with obsessive-compulsive disorder].

    PubMed · 2024-08-27 · 1 citations

    articleSenior author

    The topological properties of the brain's functional network in children and adolescents with OCD exhibit abnormalities, indicating an immature state of brain functional connectivity.

  • Facile access to 2-hydroxy-2-substituted indole-3-ones <i>via</i> a copper-catalyzed oxidative cyclization of 2-arylethynylanilines

    Chemical Communications · 2023-01-01 · 7 citations

    article

    A versatile approach towards 2-hydroxy-2-substituted indol-3-ones via a copper-catalyzed radical cyclization of 2-arylethynylanilines in the presence of O 2 has been developed. The products can be transformed to 3-hydroxy-3-substituted indol-2-ones.

  • Abnormalities of Regional Brain Activity in Patients With Schizophrenia: A Longitudinal Resting-State fMRI Study

    Schizophrenia Bulletin · 2023 · 39 citations

    • Medicine
    • Internal medicine
    • Cardiology

    BACKGROUND: Evidence from functional and structural research suggests that abnormal brain activity plays an important role in the pathophysiology of schizophrenia (SZ). However, limited studies have focused on post-treatment changes, and current conclusions are inconsistent. STUDY DESIGN: We recruited 104 SZ patients to have resting-state functional magnetic resonance imaging scans at baseline and 8 weeks of treatment with second-generation antipsychotics, along with baseline scanning of 86 healthy controls (HCs) for comparison purposes. Individual regional homogeneity (ReHo), amplitude of low-frequency fluctuations (ALFF), and degree centrality values were calculated to evaluate the functional activity. The Positive and Negative Syndrome Scale (PANSS) and MATRICS Consensus Cognitive Battery were applied to measure psychiatric symptoms and cognitive impairment in SZ patients. RESULTS: Compared with HCs at baseline, SZ patients had higher ALFF and ReHo values in the bilateral inferior temporal gyrus, inferior frontal gyrus, and lower ALFF and ReHo values in fusiform gyrus and precuneus. Following 8 weeks of treatment, ReHo was increased in right medial region of the superior frontal gyrus (SFGmed) and decreased in the left middle occipital gyrus and the left postcentral gyrus. Meanwhile, ReHo of the right SFGmed was increased after treatment in the response group (the reduction rate of PANSS ≥50%). Enhanced ALFF in the dorsolateral of SFG correlated with improvement in depressive factor score. CONCLUSIONS: These findings provide novel evidence for the abnormal functional activity hypothesis of SZ, suggesting that abnormality of right SFGmed can be used as a biomarker of treatment response in SZ.

  • Rh(<scp>iii</scp>)-catalyzed redox-neutral C–H alkenylation of benzamides with <i>gem</i>-difluorohomoallylic silyl ethers <i>via</i> β-H elimination

    Chemical Communications · 2023-01-01 · 8 citations

    article

    A practical Rh( iii )-catalyzed, redox-neutral C–H alkenylation of benzamides with gem -difluorohomoallylic silyl ethers enables the synthesis of 2-(3,3-difluoro-4-(silyloxy)but-1-en-1-yl)benzamides with a broad substrate scope and high regioselectivity.

  • Bicyclic Amidine-Triggered Cyclization of <i>o</i>-Alkynylisocyanobenzenes: Synthesis of Lactam-Derived Quinolines

    The Journal of Organic Chemistry · 2023-06-14 · 11 citations

    article

    Efficient access to the synthesis of lactam-derived quinoline through a bicyclic amidine-triggered cyclization reaction from readily prepared o-alkynylisocyanobenzenes has been developed. The reaction was initiated by nucleophilic attack of the bicyclic amidines to o-alkynylisocyanobenzenes, subsequently with intramolecular cyclization to produce a DBU-quinoline-based amidinium salt, followed by hydrolysis to afford the lactam-derived quinoline in moderate to good yields.

  • Charge‐Transfer Polymeric Hydrogels with Self‐Healing, Injectable, Thermosensitive, Adhesive, and Antibacterial Properties for Diabetic Wound Healing

    Advanced Materials Technologies · 2023-01-29 · 11 citations

    articleOpen access

    Abstract Charge transfer (CT) complexes are self‐assembled structures with a variety of attractive properties, but little is known about their performance in the construction of polymeric hydrogels. Herein, a series of hydrogels (CT‐hydrogels) with CT complex are designed and synthesized. The CT complex, consisting of pyranine derivative (sodium 8‐((4‐vinylbenzyl)oxy)pyrene‐1,3,6‐trisulfonate, VB‐HPTS) and viologen derivative (1‐methyl‐1′‐(4‐vinylbenzyl)‐[4,4′‐bipyridine]‐1,1′‐diium chloride iodide, VB‐MV), serves as the cross‐linker, and N‐(2‐hydroxyethyl)acrylamide is used as the backbone monomer. The CT complex allows CT‐hydrogels to have rapid self‐healing property, injectability, thermosensitivity, good adhesive strength on skin, and excellent antibacterial performance against both Gram‐negative and Gram‐positive bacteria. In addition, they have good biocompatibility and long‐term stability in both ambient and aqueous environments, showing potential application as wound dressing. Their performance in diabetic wound healing displays high wound healing rate, effectively inhibits inflammatory infiltration, and promotes neovascularization as compared with commercial wound dressings. The results of this study suggest that the multifunctional CT‐hydrogels are of great value in wound healing, and show a promising future to design hydrogels with CT complexes.

  • Management of Strabismus Disorders in Patients With Systemic Diseases

    Journal of Pediatric Ophthalmology & Strabismus · 2022-09-01

    article
  • Preparation and application of a specific single-chain variable fragment against artemether

    Journal of Pharmaceutical and Biomedical Analysis · 2022-08-28 · 5 citations

    articleOpen accessSenior authorCorresponding

Frequent coauthors

Education

  • M.D.

    Beijing Medical University

    1981
  • M.S.

    Beijing Medical School

  • B.S.

    Inner Mongolia Medical School

    1975
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